Anatomy and physiology of the liver and kidney

This chapter will offer the student a brief overview of the anatomy of the human liver. This e-learning will be followed by an insight in the anatomy of the donor liver, physiology, histology and liver function ex-vivo during the online class. The knowledge of this chapter will form the foundation for all the following chapters. In order to keep this e-learning as interactive as possible, after most of the subparagraphs you can expect questions to be asked on the content you have just read. Learning goals: the student can explain the anatomy of a donor organ; the student can identify relevant histological (ab)normalities. The UMCG Transplant Center has created this e-learning and is primary responsible for the quality and relevance of the content. For substantive questions you can contact your teacher or send an email to organperfusion@umcg.nl For functional questions you can send an e-mail to e-learning@umcg.nl. Press 'Start Module' to get started.

This chapter will offer you a brief overview of the anatomy of the kidney, followed by an insight in renal physiology and histology. You will gain knowledge on the most important aspects of these three domains. Lastly, an overview is given on ways to assess the kidney function. The knowledge of this chapter will form the foundation for all the following chapters. In order to keep this e-learning as interactive as possible, after most of the subparagraphs you can expect questions to be asked on the content you have just read. Learning goals: you can explain the in-vivo function of the organ; you can discuss ex vivo organ function; you can identify relevant histological (ab)normalities; you can explain how renal function is maintained and influenced in vivo and how this is different during ex vivo normothermic and hypothermic perfusion; you can explain the anatomy of a donor organ. The UMCG Transplant Center has created this e-learning and is primary responsible for the quality and relevance of the content. For substantive questions you can contact your teacher or send an email to organperfusion@umcg.nl For functional questions you can send an e-mail to e-learning@umcg.nl. Press 'Start Module' to get started.

Anatomy and physiology of the heart and lungs

This chapter will offer you a brief overview of the anatomy of the heart will be given followed by an insight in the energy metabolism. You will gain knowledge on the normal and abnormal heart rhythms and on conduction disturbances. Lastly, an overview is given on ways to assess the heart function. The knowledge of this chapter will form the foundation for all the following chapters. In order to keep this e-learning as interactive as possible, after most of the subparagraphs you can expect questions to be asked on the content you have just read. The UMCG Transplant Center has created this e-learning and is primary responsible for the quality and relevance of the content. For substantive questions you can contact your teacher or send an email to organperfusion@umcg.nl For functional questions you can send an e-mail to e-learning@umcg.nl. Press 'Start Module' to get started.

The UMCG Transplant Center has created this e-learning and is primary responsible for the quality and relevance of the content. For substantive questions you can contact your teacher or send an email to organperfusion@umcg.nl For functional questions you can send an e-mail to e-learning@umcg.nl. Press 'Start Module' to get started.

Procurement and backtable of the lungs, Heart perfusion strategies and remote and centralized EVLP

The student will learn about the anatomy of the lungs (arteries/bronchus/veins). This makes it possible to identify relevant macroscopic variations and abnormalities during the back table procedure. It also anticipates on different cannulation strategies. Learning goals: The student can explain and identify the vascular and bronchial anatomy of the organ The student can identify relevant macroscopic variation and/or abnormalities The student can demonstrate how to cannulate the organ for perfusion anticipating on every anatomical variation The student can explain a thoracic DBD and DCD procedure The student can explain the course of a surgical back table procedure during the multi-organ donation The student can explain the course of a surgical back table procedure during the inspection of the organ prior to the perfusion The UMCG Transplant Center has created this e-learning and is primary responsible for the quality and relevance of the content. For substantive questions you can contact your teacher or send an email to organperfusion@umcg.nl For functional questions you can send an e-mail to e-learning@umcg.nl. Press 'Start Module' to get started.

heart and lung: the donor and recipient, liver perfusion: NMP

This chapter will offer the student a overview on the assessment of donor hearts and donor acceptation criteria. Indications for heart transplantation are described as well as recipeint characteristics that contraindicate transplantation. In order to keep this e-learning as interactive as possible, after most of the subparagraphs you can expect questions to be asked on the content you have just read. The UMCG Transplant Center has created this e-learning and is primary responsible for the quality and relevance of the content. For substantive questions you can contact your teacher or send an email to organperfusion@umcg.nl For functional questions you can send an e-mail to e-learning@umcg.nl. Press 'Start Module' to get started.

Learning goals The student can explain the contra-indications for organ donation The student can identify risk factors for transplantation of an organ based on the information in a donor report. The student can discuss causes for end stages of renal/liver/lung disease and indications for organ transplantation. The student can explain the ET allocation system and HLA matching/MELD scoring system. Study load The study load of this module amounts 1 hour. The UMCG Transplant Center has created this e-learning and is primary responsible for the quality and relevance of the content. For substantive questions you can contact your teacher or send an email to organperfusion@umcg.nl For functional questions you can send an e-mail to e-learning@umcg.nl. Press 'Start Module' to get started.

Normothermic Machine Perfusion (NMP) is a perfusion technique that is performed for viability testing of the liver. The UMCG Transplant Center has created this e-learning and is primary responsible for the quality and relevance of the content. For substantive questions you can contact your teacher or send an email to organperfusion@umcg.nl For functional questions you can send an e-mail to e-learning@umcg.nl. Press 'Start Module' to get started.

State of the art overview per organ, thoracic perfusion machines, abdominal perfusion machines, viability testing

Learning goals: The students can explain the anatomical structures of the liver relevant to machine perfusion. The student can explain the surgical techniques of the backtable. The student can explain how to attach the cannulas. The student can explain the different flushes and the technique behind this. The student can explain the differences between the DHOPE and NMP backtable. The student can explain the correct position of the liver on the machine. The student can explain the technique for connecting the liver to the machine. The student can explain backtable procedure during the switch. The UMCG Transplant Center has created this e-learning and is primary responsible for the quality and relevance of the content. For substantive questions you can contact your teacher or send an email to organperfusion@umcg.nl For functional questions you can send an e-mail to e-learning@umcg.nl. Press 'Start Module' to get started.

This chapter will offer the student a bief overview of the procurement sequence including the backtable procedure. Surgical differences between DBD and DCD are highlighted and the basics of cardioplegia are overviewed. In order to keep this e-learning as interactive as possible, after most of the subparagraphs you can expect questions to be asked on the content you have just read. The UMCG Transplant Center has created this e-learning and is primary responsible for the quality and relevance of the content. For substantive questions you can contact your teacher or send an email to organperfusion@umcg.nl For functional questions you can send an e-mail to e-learning@umcg.nl. Press 'Start Module' to get started.

liver and kidney: the donor and the recipient

Chapters 3 and 4 focus on the donor and on the recipient. This e-learning module will specifically highlight aspects of liver donation, donor-to-recipient allocation, and patients with end-stage liver disease, i.e., liver transplant recipients. Learning goals: The student can explain the contra-indications for liver donation. The student can identify risk factors for transplantation of a liver based on the information in a donor report. The student can discuss causes for end stages of liver disease and indications for liver transplantation The student can explain the ET allocation system and MELD scoring system for the liver This e-learning will focus on learning goals 3 and 4, the recipient. The UMCG Transplant Center has created this e-learning and is primary responsible for the quality and relevance of the content. For substantive questions you can contact your teacher or send an email to organperfusion@umcg.nl For functional questions you can send an e-mail to e-learning@umcg.nl. Press 'Start Module' to get started.

Chapters 3 and 4 focus on the donor and on the recipient. This e-learning module will specifically highlight aspects of kidney donation, donor-to-recipient matching and renal patients, i.e. kidney recipients. Learning goals: The student can explain the contra-indications for kidney donation. The student can identify risk factors for transplantation of an organ based on the information in a donor report. The student can discuss causes for end stage renal disease and indications for organ transplantation. The student can explain the ET allocation system and HLA matching. In order to keep this e-learning as interactive as possible, after most of the subparagraphs you can expect questions to be asked on the content you have just read. The UMCG Transplant Center has created this e-learning and is primary responsible for the quality and relevance of the content. For substantive questions you can contact your teacher or send an email to organperfusion@umcg.nl For functional questions you can send an e-mail to e-learning@umcg.nl. Press 'Start Module' to get started.

Troubleshooting

Transplantation and follow-up

NRP, Run your own perfusion, Troubleshooting, Symposium

Normothermic Regional Perfusion (NRP) is a perfusion technique that is performed in a DCD donor at the donor hospital. Currently, aNRP is used in both uDCD and cDCD donors in several countries, such as Spain, United Kingdom, Norway, France, and Italy. After death is declared, the donor is cannulated on either the OR or on the ICU and NRP is started. There are two forms of NRP: Abdominal NRP (aNRP) Thoracoabdominal NRP (taNRP) Main learning objectives Introduction to NRP: why and when The basics of the NRP circuit How to perform NRP and perfusion goals The basics of blood gas and chemical analysis 5. Viability assessment of the liver The UMCG Transplant Center has created this e-learning and is primary responsible for the quality and relevance of the content. For substantive questions you can contact your teacher or send an email to organperfusion@umcg.nl For functional questions you can send an e-mail to e-learning@umcg.nl. Press 'Start Module' to get started.